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Hello, my name is Christophe Klopp,

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and I will explain what Sigenae is.

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Sigenae is a platform of engineers,

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which was set up

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20 years ago,

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and which provides services to biologists

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interested in farm animals at INRAE.

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These engineers are located on two sites,

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as shown on the map,

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and belong to 4 departments:

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Animal Genetics (GA),

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Animal Physiology and Breeding System (PHASE),

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Animal Health (SA) and

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Mathematics and Numeracy (MathNum).

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What services does Sigenae provide?

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First of all, the first service,

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which corresponds to most of our working time,

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is the processing of massive data,

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mainly from 2nd and 3rd generation sequencers.

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And in terms of applications,

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we are focused on variant calling

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from genomes or pieces of genomes or even transcriptomes,

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on the assembly (genomes or transcriptomes),

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we do diversity research (16S),

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we perform a lot of expression analysis, expression quantification.

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We store genotypes and variants, and perform small RNAs analyses.

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We participate in major projects,

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such as the 1000 bovine genomes or VarGoats,

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we have assembled the bee

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or many fishes (in progress).

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Another part of our activity is the development of

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software and databases.

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I have put two examples of software

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here on the slide: jVenn and D-Genies.

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JVenn is a software which allows you

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to make Venn diagrams from lists

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and D-Genies is a software which

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compares genomes and presents dotplots.

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And I have also added the PhyloFish database,

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which is a database of transcriptomes of 20 fishes

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on 10 tissues, allowing you to

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visualise transcripts, annotations

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and variants in these transcripts.

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It is a rather rich database.

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The third part of our activity is training.

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We are trainers in the Genotoul bioinfo training courses,

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we work on calling variants

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as well as on the RNAseq and then

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on the various assembly modules.

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Sigenae also maintains the Galaxy environment

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for the Genotoul community.

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We administer the machine, manage the tickets...

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And in conclusion: what can Sigenae do for you?

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Discuss your projects,

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discuss techniques,

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train you in bioinformatics and

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help you with data processing.

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Thank you, see you soon.